Advanced Search

Show simple item record

dc.contributor.authorKamacı, Musa
dc.contributor.authorKaya, İsmet
dc.date.accessioned2021-09-23T11:42:26Z
dc.date.available2021-09-23T11:42:26Z
dc.date.issued2021en_US
dc.identifier.citationKamaci, M., & Kaya, I. (2021). Preparation of biodegradable, and pH-sensitive poly (azomethine)-chitosan hydrogels for potential application of 5-fluoro uracil delivery. European Polymer Journal, 158, 110680, p. 1-11 .en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12960/1272
dc.description.abstractIn this paper, we aimed to prepare poly(azomethine) and chitosan-based hydrogels for the controlled drug delivery applications. For this purpose, poly(azomethine)s were prepared by oxidative polymerization and they were characterized via using FT-IR, 1H NMR, 13C NMR, and SEC analysis techniques. Then, poly(azomethine)s and chitosan-based hydrogels were prepared in the presence of 1,4-butanediol, and ammonium peroxodisulphate as chain extender, and initiator, respectively, and they were also characterized using FT-IR. The mechanical, thermal, morphological, swelling, biodegradability, antibacterial properties, and the controlled drug delivery application were carried out in the paper. The obtained results revealed that the fabricated hydrogels have consisted of a non-porous structure. The thermal stability of the hydrogels was decreased with the addition of chitosan into the hydrogel matrix. Moreover, poly(azomethine) and chitosan-based hydrogels were exhibited biodegradable, antibacterial, and pH-sensitive properties, and they have a potential application of the release of 5-FU.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.ispartofEuropean Polymer Journalen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectPoly(azomethine)en_US
dc.subjectChitosanen_US
dc.subject5-fluoro uracilen_US
dc.subjectpH sensitiveen_US
dc.subjectBiodegradableen_US
dc.titlePreparation of biodegradable, and pH-sensitive poly(azomethine)-chitosan hydrogels for potential application of 5-fluoro uracil deliveryen_US
dc.typearticleen_US
dc.authorid0000-0001-5865-7687en_US
dc.departmentMühendislik Fakültesi, Elektrik-Elektronik Mühendisliği Bölümüen_US
dc.contributor.institutionauthorKamacı, Musa
dc.identifier.volume158en_US
dc.identifier.startpage1en_US
dc.identifier.endpage11en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record