Yazar "Öz, Umut Can" için listeleme
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Design of Colloidally Stable and Non-Toxic Petox-Based Polymersomes for Cargo Molecule Encapsulation
Öz, Umut Can; Küçüktürkmen, Berrin; Özköse, Umut Uğur; Gülyüz, Sevgi; Bolat, Zeynep Büşra; Telci, Dilek (Wiley-V C H Verlag Gmbh, 2019)Polymersomes are vesicular constructs formed by the self-assembly of polymer amphiphiles. Here we report the fabrication of PEtOx-b-PLA polymersomes at physiological pH/salt concentration and the determination of a f(PEtOx) ... -
Design of Polymeric Nanoparticles for Theranostic Delivery of Capsaicin as Anti-Cancer Drug and Fluorescent Nitrogen-Doped Graphene Quantum Dots
Küçüktürkmen, Berrin; Öz, Umut Can; Er, Engin; Gómez, I. Jénnifer; Tekneci, Seda İpek; Eşim, Özgür; Özköse, Umut Uğur; Gülyüz, Sevgi; Üstündağ, Aylin; Yılmaz, Özgür; Zajíčková, Lenka; Bozkır, Asuman (John Wiley and Sons Inc., 2024)In recent years, multifunctional nanocarriers that provide simultaneous drug delivery and imaging have attracted enormous attention, especially in cancer treatment. In this research, a biocompatible fluorescent multifunctional ... -
Development of self-assembled poly(2-ethyl-2-oxazoline)-b-poly(epsilon-caprolactone) (PEtOx-b-PCL) copolymeric nanostructures in aqueous solution and evaluation of their morphological transitions
Özköse, Umut Uğur; Gülyüz, Sevgi; Öz, Umut Can; Taşdelen, Mehmet Atilla; Alptürk, Onur; Bozkır, Asuman (Budapest Univ Technol & Econ, 2020)Amphiphilic block copolymers are known to self-assemble into various morphologies, including ellipsoids, tubular structures, toroids, vesicles, micellar structures. In this paper, we discuss the synthesis of copolymeric ... -
A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomes
Öz, Umut Can; Bolat, Zeynep Büşra; Özköse, Umut Uğur; Gülyüz, Sevgi; Küçüktürkmen, Berrin; Khalily, Melek Parlak (Elsevier, 2021)The equipping of nanoparticles with the peptide moiety recognizing a particular receptor, enables cell or tissue specific targeting, therefore the optimization of the targeted nanoparticles is a key factor in the formulation ... -
The Utilization of Poly(2-ethyl-2-oxazoline)-b-Poly(epsilon-caprolactone) Ellipsoidal Particles for Intracellular BIKDDA Delivery to Prostate Cancer
Koçak, Polen; Öz, Umut Can; Bolat, Zeynep Büşra; Özköse, Umut Uğur; Gülyüz, Sevgi; Taşdelen, Mehmet Atilla (Wiley-V C H Verlag Gmbh, 2021)Prostate cancer is the most common cancer, which is about 15-20% among male cancers worldwide. As most common strategies such as radiotherapy, chemotherapy, or surgery alone can be unsuccessful in the treatment of prostate ...
