Yazar "Bolat, Zeynep Büşra" için WoS İndeksli Yayınlar Koleksiyonu listeleme
-
Delivery of doxorubicin loaded P18 conjugated-poly(2-ethyl-oxazoline)-DOPE nanoliposomes for targeted therapy of breast cancer
Bolat, Zeynep Büşra; Nezir, Ayça Ece; Devrim, Burcu; Zemheri, Ebru; Gülyüz, Sevgi; Özköse, Umut Uğur; Yılmaz, Özgür; Bozkır, Asuman; Telci, Dilek; Şahin, Fikrettin (Elsevier, 2021)Breast cancer, a heterogeneous disease, has the highest incidence rate and is a major cause of death in females worldwide. Drug delivery by using nanotechnology has shown great promise for improving cancer treatment. ... -
Design and evaluation of peptide-18-targeted nanoliposomes constructed by poly(2-oxazoline)-DOPE for doxorubicin delivery
Devrim, Burcu; Bolat, Zeynep Büşra; Telci, Dilek; Şahin, Fikrettin; Gülyüz, Sevgi; Özköse, Umut Uğur (Taylor & Francis Ltd, 2021)Aims The aim of this study is to develop targeted nanoliposome formulations to provide efficient treatment for breast cancer. In this study, peptide 18-modified poly(2-ethyl-2-oxazoline)-dioleoylphosphatidylethanolamine ... -
Design of Colloidally Stable and Non-Toxic Petox-Based Polymersomes for Cargo Molecule Encapsulation
Öz, Umut Can; Küçüktürkmen, Berrin; Özköse, Umut Uğur; Gülyüz, Sevgi; Bolat, Zeynep Büşra; Telci, Dilek (Wiley-V C H Verlag Gmbh, 2019)Polymersomes are vesicular constructs formed by the self-assembly of polymer amphiphiles. Here we report the fabrication of PEtOx-b-PLA polymersomes at physiological pH/salt concentration and the determination of a f(PEtOx) ... -
Poly(2-ethyl-2-oxazoline-co-ethyleneimine)-block-poly(epsilon-caprolactone) based micelles: synthesis, characterization, peptide conjugation and cytotoxic activity
Gülyüz, Sevgi; Özköse, Umut Uğur; Khalily, Melek Parlak; Kesici, Mehmet Seçkin; Koçak, Polen; Bolat, Zeynep Büşra; Kara, Aslı; Öztürk, Naile; Özçubukçu, Salih; Bozkır, Asuman; Alptürk, Onur; Telci, Dilek; Şahin, Fikrettin; Vural, İmran; Yılmaz, Özgür (Royal Society of Chemistry, 2021)Here we present self-assembled polymeric micelles as potential delivery systems for therapeutic agents with highly tunable properties. The major goal of this study is to design breast and prostate cancer specific targeting ... -
A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomes
Öz, Umut Can; Bolat, Zeynep Büşra; Özköse, Umut Uğur; Gülyüz, Sevgi; Küçüktürkmen, Berrin; Khalily, Melek Parlak (Elsevier, 2021)The equipping of nanoparticles with the peptide moiety recognizing a particular receptor, enables cell or tissue specific targeting, therefore the optimization of the targeted nanoparticles is a key factor in the formulation ... -
The Utilization of Poly(2-ethyl-2-oxazoline)-b-Poly(epsilon-caprolactone) Ellipsoidal Particles for Intracellular BIKDDA Delivery to Prostate Cancer
Koçak, Polen; Öz, Umut Can; Bolat, Zeynep Büşra; Özköse, Umut Uğur; Gülyüz, Sevgi; Taşdelen, Mehmet Atilla (Wiley-V C H Verlag Gmbh, 2021)Prostate cancer is the most common cancer, which is about 15-20% among male cancers worldwide. As most common strategies such as radiotherapy, chemotherapy, or surgery alone can be unsuccessful in the treatment of prostate ...