• The use of graphene nanoplatelet-embedded PA-6 nanofibres to remove turbidity from water 

  Zembat, Ahmet Alp; Gezmis-Yavuz, Elifnur; Köseoğlu-İmer, Derya Y.; Cansoy, C. Elif (John Wiley and Sons Inc, 2025)

  The global challenge of providing clean water at an affordable cost has led to the need for the development of low-cost and non-toxic materials for the treatment and recycling of waste water. Nanofibres have emerged as a ...

• Fabrication of electrospun graphene-oxide embedded polyacrylonitrile composite nanofibers for air filtration 

  Demir, Gamze; Gezmiş-Yavuz, Elifnur; Zembat, Ahmet Alp; Koseoglu-Imer, Derya Y.; Cansoy, C. Elif (Taylor and Francis Ltd., 2025)

  In this study, polyacrylonitrile-graphene oxide (PAN/GO) nanofiber composite nanofibers were prepared with varying GO ratios between 0.1 and 0.5 wt% by electrospinning technique. The fiber diameter of bare PAN was increased ...

• Delivery of BikDD proapoptotic gene in Peptide-18-targeted Poly(2-oxazoline)-DOPE nanoliposomes for breast cancer models 

  Bolat, Zeynep Büşra; Nezir, Ayça Ece; Saka, Ongun Mehmet; Zemheri, Itır Ebru; Gülyüz, Sevgi; Özköse, Umut Uğur; Yılmaz, Özgür; Bozkır, Asuman; Telci, Dilek; Şahin, Fikrettin (TUBITAK, 2024)

  Breast cancer is one of the most common cancers and a significant cause of death in females worldwide. For effective breast cancer treatment, using systems with a promising delivery of anticancer agents is an important ...

• Deeper Spectroscopic Characterizations of Vinylidene Fluoride (VDF) Oligomers Prepared via Iodine Transfer Polymerization (ITP) 

  Özköse, Umut Uğur; Pacholski, Pierre; Gimello, Olinda; Schramm, Sebastien; Aubriet, Frederic; Progent, Frederic; Ameduri, Bruno (Amer Chemical Soc., 2024)

  The iodine transfer polymerization of vinylidene fluoride (or 1,1-difluoroethylene, VDF) controlled by 1-iodoperfluoroalkanes or 1,8-diiodoperfluoroctane led to oligo(VDF)s containing one or two iodine end-atom(s). Their ...

• PEtOx-DOPE nanoliposomes functionalized with peptide 563 in targeted BikDDA delivery to prostate cancer 

  Nezir, Ayca Ece; Bolat, Zeynep Büşra; Saka, Ongun Mehmet; Zemheri, Itır Ebru; Gülyüz, Sevgi; Özköse, Umut Uğur; Yilmaz, Özgür; Bozkir, Asuman; Şahin, Fikrettin; Telci, Dilek (TUBITAK, 2024)

  Background: Nanocarrier-based systems have cultivated significant improvements in prostate cancer therapy. However, the efforts are still limited in clinical applicability, and more research is required for the development ...

• Combined DFT and ionic model computational study of the effect of alkali metal cations on the structure, bonding and properties of molten cryolites, M3AlF6 (M = li, Na, K, Rb, and Cs) 

  Özen, Alimet Sema; Akdeniz, Zehra (Taylor and Francis Ltd., 2024)

  Ionic melts, in the form of ionic liquids and molten salts, are important in many technological aspects such as metal production and energy applications. Cryolite melts constitute an important family especially for the ...

• Synthesis of Calamitic Fluorinated Mesogens with Complex Crystallization Behavior 

  Anokhin, Denis; Maryasevskaya, Alina; Abukaev, Ainur; Ozkose, Umut Ugur; Buglakov, Alexander; Ivanov, Dimitri A.; Améduri, Bruno (Multidisciplinary Digital Publishing Institute (MDPI), 2023)

  This work presents the synthesis and self-organization of the calamitic fluorinated mesogen, 1,1,2,2–tetrafluoro–2–(1,1,2,2–tetrafluoro–4–iodobutoxy)ethanesulfonic acid, a potential model for perfluorosulfonic acid membranes ...

• Targeting prostate cancer with docetaxel-loaded peptide 563-conjugated PEtOx-co-PEI30%-b-PCL polymeric micelle nanocarriers 

  Nezir, Ayca Ece; Bolat, Zeynep Busra; Ozturk, Naile; Kocak, Polen; Zemheri, Ebru; Gulyuz, Sevgi; Özköse, Umut Uğur; Yilmaz, Ozgur; Vural, Imran; Bozkır, Asuman; Şahin, Fikrettin; Telci, Dilek (Springer, 2023)

  Prostate cancer is a global disease that negatively affects the quality of life. Although various strategies against prostate cancer have been developed, only a few achieved tumor-specific targeting. Therefore, a special ...

• Synthesis and characterization of benzodioxinone-bearing methacrylate-based random copolymer via atom transfer radical polymerization 

  Çelik, Cumali; Açık, Gökhan (Tübitak Dergi Park, 2021)

  Methacrylate-benzodioxinone (BDMA) as a monomer was firstly synthesized and then copolymerized with methyl methacrylate and 2-hydroxyethyl methacrylate via atom transfer radical polymerization (ATRP) in the presence of ...

• Biodegradable and antibacterial chlorinated polypropylene/chitosan based composite films for biomedical applications 

  Açık, G.; Altınkök, Ç.; Açık, B. (Springer, 2022)

  Chlorinated polypropylene (PP-Cl)-chitosan (Cs) composite films (PP-Css) are prepared at different proportions (PP-Cl:Cs (w:w) = 2:1, 1:1, 1:2) by solution casting method as a candidate for biomedical applications. PP-Cs ...

• Preparation of a sustainable bio-copolymer based on Luffa cylindrica cellulose and poly(ɛ-caprolactone) for bioplastic applications 

  Akay, Özge; Altınkök, Çağatay; Açık, Gökhan; Yüce, Hüseyin; Konuk Ege, Gözde; Genç, Garip (Elsevier, 2022)

  In this research, a bio-based graft copolymer (LCC-g-PCL) based on the cellulose of Luffa cylindrica (LCC) main chain possessing poly(ɛ-caprolactone) (PCL) pendant groups is synthesized through a grafting from approach via ...

• Design and evaluation of peptide-18-targeted nanoliposomes constructed by poly(2-oxazoline)-DOPE for doxorubicin delivery 

  Devrim, Burcu; Bolat, Zeynep Büşra; Telci, Dilek; Şahin, Fikrettin; Gülyüz, Sevgi; Özköse, Umut Uğur; Yılmaz, Özgür; Bozkır, Asuman (Taylor and Francis, 2021)

  Aims: The aim of this study is to develop targeted nanoliposome formulations to provide efficient treatment for breast cancer. In this study, peptide 18-modified poly(2-ethyl-2-oxazoline)-dioleoylphosphatidylethanolamine ...

• Layer-by-Layer Assembled, Amphiphilic and Antibacterial Hybrid Electrospun Mat Made from Polypropylene and Chitosan Fibers 

  Açık, Gökhan; Açık, Burcu; Agel, Esra (Springer, 2021)

  In this study, hybrid fiber mat (HFPP-CS) consisting of both chlorinated polypropylene and chitosan fibers (FPP-Cl and FCS) is obtained by assembling layer-by-layer for the first time using electrospinning process. ...

• Delivery of doxorubicin loaded P18 conjugated-poly (2-ethyl-oxazoline)-DOPE nanoliposomes for targeted therapy of breast cancer 

  Bolat, Zeynep Busra; Nezir, Ayca Ece; Devrim, Burcu; Zemheri, Ebru; Gulyuz, Sevgi; Ozkose, Umut Ugur; Bozkir, Asuman; Telci, Dilek; Sahin, Fikrettin (Elsevier, 2021)

  Breast cancer, a heterogeneous disease, has the highest incidence rate and is a major cause of death in females worldwide. Drug delivery by using nanotechnology has shown great promise for improving cancer treatment. ...

• Fabrication of polypropylene fibers possessing quaternized ammonium salt based on the combination of CuAAC click chemistry and electrospinning 

  Açık, Gökhan (Elsevier, 2021)

  This study provides a straightforward method for preparing fibers of polypropylene possessing quaternary ammonium salt (FPP-QAS) by combining copper (I)-catalyzed azide-alkyne cycloaddition “click” reaction (CuAAC) and ...

• Synthesis and characterization of bile acid-based polymeric micelle as a drug carrier for doxorubicin 

  Altınkök, Çağatay; Açık, Gökhan; Karabulut, Hüseyin Rıza Ferhat; Çiftçi, Mustafa; Taşdelen, Mehmet Atilla; Dağ, Aydan (John Wiley and Sons, 2021)

  In the present study, a polymeric micelle based on amphiphilic block copolymer, namely poly(methacrylated methyl lithocholate)-block-poly(oligoethylene glycol methacrylate) (PMML-b-POEGMA) bearing bile acid moiety is ...

• Delivery of doxorubicin loaded P18 conjugated-poly(2-ethyl-oxazoline)-DOPE nanoliposomes for targeted therapy of breast cancer 

  Bolat, Zeynep Büşra; Nezir, Ayça Ece; Devrim, Burcu; Zemheri, Ebru; Gülyüz, Sevgi; Özköse, Umut Uğur; Yılmaz, Özgür; Bozkır, Asuman; Telci, Dilek; Şahin, Fikrettin (Elsevier, 2021)

  Breast cancer, a heterogeneous disease, has the highest incidence rate and is a major cause of death in females worldwide. Drug delivery by using nanotechnology has shown great promise for improving cancer treatment. ...

• Poly(2-ethyl-2-oxazoline-co-ethyleneimine)-block-poly(epsilon-caprolactone) based micelles: synthesis, characterization, peptide conjugation and cytotoxic activity 

  Gülyüz, Sevgi; Özköse, Umut Uğur; Khalily, Melek Parlak; Kesici, Mehmet Seçkin; Koçak, Polen; Bolat, Zeynep Büşra; Kara, Aslı; Öztürk, Naile; Özçubukçu, Salih; Bozkır, Asuman; Alptürk, Onur; Telci, Dilek; Şahin, Fikrettin; Vural, İmran; Yılmaz, Özgür (Royal Society of Chemistry, 2021)

  Here we present self-assembled polymeric micelles as potential delivery systems for therapeutic agents with highly tunable properties. The major goal of this study is to design breast and prostate cancer specific targeting ...

• Superhydrophobic EVA copolymer fibers: the impact of chemical composition on wettability and photophysical properties 

  Açık, Gökhan; Kamacı, Musa; Özen Cansoy, C. Elif (Springer, 2018)

  Fibers of poly(vinyl acetate) (PVAc) homopolymer and ethylene vinyl acetate (EVA) copolymers with varying vinyl acetate (VAc) contents between 25 and 40wt.% have been prepared to investigate wettability and photophysical ...

• Synthesis of fluorinated polypropylene using CuAAC click chemistry 

  Açık, Gökhan; Özen Cansoy, C. Elif; Taşdelen, Mehmet Atilla (Wiley, 2019)

  Synthesis of fluorine containing polypropylene (PP-F) from chlorinated polypropylene (PP-Cl) via Cu(I) catalyzed Huisgen type 1,3-dipolar cycloaddition (CuAAC) and its water repellency properties are demonstrated. Initially, ...

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