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dc.contributor.authorKamacı, Ümran Duru
dc.contributor.authorKamacı, Musa
dc.contributor.authorPeksel, Ayşegül
dc.date.accessioned2021-06-05T19:56:19Z
dc.date.available2021-06-05T19:56:19Z
dc.date.issued2019
dc.identifier.issn1386-1425
dc.identifier.urihttps://doi.org/10.1016/j.saa.2019.01.011
dc.identifier.urihttps://hdl.handle.net/20.500.12960/238
dc.description0000-0001-5865-7687en_US
dc.description0000-0003-2650-9107en_US
dc.description0000-0003-3881-8513en_US
dc.descriptionPubMed: 30641363en_US
dc.descriptionWOS:000471307100029en_US
dc.description.abstractIn the present paper, a highly selective and sensitive fluorescent biosensor based on poly(azomethine-urethane) and zeolite for the determination of DNA molecules was developed. Zeolite was chosen to enhance with anionic or cationic functional groups in polymer matrix and interaction between polymer and DNA. Several parameters such as polymer concentration, pH and incubation time effect on the sensitivity of the fluorescent biosensor were optimized. Linear range was determined between 2.50 and 25.00 nmol/L DNA concentration and limit of detection (LOD) of the biosensor was calculated as 0.095 nmol/L under the optimal conditions. Interference study was also performed in the presence of different amino adds, cations and organic compounds. The results dearly indicated that the tested cations and compounds were not induced a significant fluorescence change and the proposed zeolite-based biosensor was shown a good selectivity for DNA. (C) 2019 Elsevier B.V. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofSpectrochimica Acta Part A-Molecular and Biomolecular Spectroscopyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectZeoliteen_US
dc.subjectDnaen_US
dc.subjectFluorescent Sensoren_US
dc.subjectBiosensoren_US
dc.titlePoly(azomethine-urethane) and zeolite-based composite: Fluorescent biosensor for DNA detectionen_US
dc.typearticleen_US
dc.departmentFen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.department-temp[Kamaci, Umran Duru; Peksel, Aysegul] Yildiz Tech Univ, Dept chem, Fac Arts & Sci, TR-34220 Istanbul, Turkey; [Kamaci, Musa] Piri Reis Univ, TR-34940 Istanbul, Turkeyen_US
dc.contributor.institutionauthorKamacı, Musa
dc.identifier.doi10.1016/j.saa.2019.01.011
dc.identifier.volume212en_US
dc.identifier.startpage232en_US
dc.identifier.endpage239en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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